{"id":1614,"date":"2025-08-30T16:47:57","date_gmt":"2025-08-30T07:47:57","guid":{"rendered":"https:\/\/nippori-lc.jp\/blog\/?p=1614"},"modified":"2025-09-01T14:18:08","modified_gmt":"2025-09-01T05:18:08","slug":"post-1614","status":"publish","type":"post","link":"https:\/\/nippori-lc.jp\/blog\/?p=1614","title":{"rendered":"\uff24\uff26\uff29\u691c\u67fb"},"content":{"rendered":"\n<p><a><\/a>\u3053\u3093\u306b\u3061\u306f\u57f9\u990a\u90e8\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u3053\u306e\u5ea6\u3001\u5f53\u9662\u3067\u65b0\u305f\u306b\u5c0e\u5165\u3057\u305f\u691c\u67fb\u306b\u3064\u3044\u3066\u3054\u7d39\u4ecb\u3057\u307e\u3059\u3002\u305d\u306e\u691c\u67fb\u306f\u300c\uff24\uff26\uff29\u691c\u67fb\u300d\u3068\u3044\u3044\u3001\u300c\u7cbe\u5b50\u306e\u8cea\u300d\u3092\u6e2c\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u3068\u3055\u308c\u3066\u3044\u3066\u3001\u8fd1\u5e74\u6ce8\u76ee\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u203bDFI\uff1aDNA Fragmentation Index<\/p>\n\n\n\n<p>\u6700\u8fd1\u3067\u306f\u304b\u306a\u308a\u30e1\u30b8\u30e3\u30fc\u306b\u306a\u3063\u3066\u304d\u3066\u304a\u308a\u3001\u3059\u3067\u306b\u3054\u5b58\u3058\u306e\u65b9\u3082\u591a\u304f\u3044\u3089\u3063\u3057\u3083\u308b\u304b\u3068\u601d\u3044\u307e\u3059\u304c\u3001\u3053\u306e\uff24\uff26\uff29\u691c\u67fb\u3067\u306f\u7cbe\u6db2\u306e\u300cDNA\u65ad\u7247\u5316\u7387\u300d\u3092\u6e2c\u5b9a\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u3001\u3053\u308c\u306b\u3088\u3063\u3066\u598a\u5a20\u306b\u9069\u3057\u305f\u7cbe\u5b50\u306e\u72b6\u614b\u3067\u3042\u308b\u304b\u3069\u3046\u304b\u3092\u77e5\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<p>DNA\u306e\u65ad\u7247\u5316\u3068\u306f\u3001DNA\u304c\u4f55\u3089\u304b\u306e\u8981\u56e0\u3067\u640d\u50b7\u3092\u53d7\u3051\u3066\u3057\u307e\u3063\u305f\u72b6\u614b\u306e\u3053\u3068\u3067\u3001\u3053\u306e\u6570\u5024\u304c\u9ad8\u3044\u3068\u6d41\u7523\u7387\u3084\u80ce\u5150\u306e\u5148\u5929\u7570\u5e38\u306a\u3069\u306b\u5f71\u97ff\u304c\u3042\u308b\u305f\u3081\u3001\u6ce8\u610f\u304c\u5fc5\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<div class=\"wp-block-group\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<p class=\"has-background\" style=\"background-color:#89b7bb33\">\uff24\uff26\uff29\u691c\u67fb\u3067\u306f\u7279\u6b8a\u306a\u6eb6\u6db2\u3092\u4f7f\u3063\u3066\u7cbe\u5b50\u306e\u7d30\u80de\u3092\u6eb6\u304b\u3057\u3001\u7cbe\u5b50\u306e\uff24\uff2e\uff21\u3092\u67d3\u8272\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-group is-content-justification-center is-nowrap is-layout-flex wp-container-core-group-is-layout-94bc23d7 wp-block-group-is-layout-flex\">\n<figure class=\"wp-block-image size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"348\" height=\"232\" src=\"https:\/\/nippori-lc.jp\/blog\/wp-content\/uploads\/2025\/08\/image-2.png\" alt=\"\" class=\"wp-image-1617\" style=\"width:362px;height:auto\"\/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"254\" height=\"232\" src=\"https:\/\/nippori-lc.jp\/blog\/wp-content\/uploads\/2025\/08\/image-3.png\" alt=\"\" class=\"wp-image-1618\" style=\"width:213px;height:auto\"\/><\/figure>\n<\/div>\n\n\n\n<p><\/p>\n\n\n\n<p>\u7cbe\u5b50\u304b\u3089\u67d3\u307f\u51fa\u305f\u300chalo\u300d\u306e\u30b5\u30a4\u30ba\u3092\u8a08\u6e2c\u3057\u3066<mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-pale-pink-color\">\u7570\u5e38\uff08\uff26\uff52\uff41\uff47\uff4d\uff45\uff4e\uff54\uff45\uff44\uff09<\/mark>DNA\u65ad\u7247\u5316\u306e\u5272\u5408\u3092\u8abf\u3079\u308b<\/p>\n\n\n\n<p>\u300cBig halo\u300d\u3068\u300cMedium halo\u300d\u3000\u2192<mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-vivid-cyan-blue-color\">\u6b63\u5e38\uff08\uff2e\uff4f\uff52\uff4d\uff41\uff4c\uff09<\/mark><\/p>\n\n\n\n<p>\u300csmall halo\u300d \u3084\u300chalo\u306a\u3057\u300d\u3000\u2192<mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-pale-pink-color\">\u7570\u5e38\uff08\uff26\uff52\uff41\uff47\uff4d\uff45\uff4e\uff54\uff45\uff44\uff09<\/mark>\u3000\u3000<mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-pale-pink-color\">\uff24\uff26\uff29\u7387\u3000\u3007\u3007\uff05<\/mark><\/p>\n\n\n\n<p>\u3053\u306e\u8d64\u304f\u67d3\u307e\u3063\u305f\u90e8\u5206\u304c\u3042\u308b\u7cbe\u5b50\u306fDNA\u304c\u6b63\u5e38\uff08Normal\uff09\u3067\u554f\u984c\u306a\u3057\u3002\u5927\u304d\u304f\u67d3\u307e\u3089\u306a\u304b\u3063\u305f\u7cbe\u5b50\u306f\u7570\u5e38\uff08Fragmented\uff09\u7b87\u6240\u304c\u3042\u308b\u7cbe\u5b50\uff08DNA\u65ad\u7247\u5316\u3057\u3066\u3044\u308b\uff09\u3068\u5224\u65ad\u3055\u308c\u307e\u3059\u3002\u3053\u306e\u5272\u5408\u3092\u307f\u3066\u8a55\u4fa1\u3057\u307e\u3059\u300230\uff05\u3092\u8d85\u3048\u308b\u3088\u3046\u306a\u6570\u5024\u3060\u3063\u305f\u5834\u5408\u3001\u598a\u5a20\u306b\u60aa\u5f71\u97ff\u304c\u3042\u308b\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u6700\u65b0\u306e\u4e16\u754c\u4fdd\u5065\u6a5f\u95a2\uff08WHO\uff09\u30e9\u30dc\u30de\u30cb\u30e5\u30a2\u30eb\u7b2c6\u7248\u3067\u306f\u3001DFI\u691c\u67fb\u306e\u6570\u5024\u304c\u8ffd\u52a0\u3055\u308c\u308b\u306a\u3069\u3001\u8fd1\u5e74\u3067\u306f\u300c\u7cbe\u5b50\u306e\u8cea\u300d\u3092\u8a55\u4fa1\u3059\u308b\u65b0\u305f\u306a\u6307\u6a19\u3068\u3057\u3066\u91cd\u8981\u8996\u3055\u308c\u3066\u3044\u308b\u308f\u3051\u3067\u3059\u304c\u3001\u5f93\u6765\u306e\u7cbe\u6db2\u691c\u67fb\u3067\u306f\u7cbe\u5b50\u306e\u300c\u6fc3\u5ea6\u300d\u3068\u300c\u904b\u52d5\u6027\u300d\u3057\u304b\u8abf\u3079\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p>\u5f53\u7136\u3001\u5f93\u6765\u306e\u691c\u67fb\u6cd5\u3067\u308f\u304b\u308b\u3001\u7cbe\u5b50\u306e\u6fc3\u5ea6\u3068\u904b\u52d5\u6027\u306f\u598a\u5a20\u7387\u306b\u306f\u5927\u304d\u304f\u5f71\u97ff\u3059\u308b\u3053\u3068\u304c\u308f\u304b\u3063\u3066\u3044\u307e\u3059\u304c\u3001\u7cbe\u5b50\u306e\u904b\u52d5\u6027\u306f\u554f\u984c\u306a\u3044\u306e\u306b\u598a\u5a20\u306b\u81f3\u3089\u306a\u304b\u3063\u305f\u308a\u3001\u6d41\u7523\u3092\u7e70\u308a\u8fd4\u3057\u3066\u3057\u307e\u3063\u305f\u308a\u3057\u3066\u3057\u307e\u3046\u4f8b\u304c\u591a\u304f\u307f\u3089\u308c\u307e\u3059\u3002\u3053\u3046\u3057\u305f\u539f\u56e0\u3068\u3057\u3066\u7cbe\u5b50\u306e\u300c\u8cea\u300d\u306e\u90e8\u5206\u3067\u3042\u308bDNA\u65ad\u7247\u5316\u7387\u306b\u5f71\u97ff\u304c\u3042\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u305f\u6765\u305f\u3053\u3068\u3067\u3001\u7cbe\u6db2\u691c\u67fb\u306e\u5fc5\u8981\u306a\u9805\u76ee\u3068\u3057\u3066\u6ce8\u76ee\u3055\u308c\u3066\u304a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u300c\u7cbe\u5b50\u306eDNA\u640d\u50b7\u306f\u3001\u80da\u767a\u751f\u306e\u9045\u5ef6\u3084\u7740\u5e8a\u7387\u306e\u4f4e\u4e0b\u3068\u95a2\u9023\u3057\u3066\u304a\u308a\u3001\u7279\u306b\u9855\u5fae\u6388\u7cbe\uff08ICSI\uff09\u306b\u304a\u3044\u3066\u9855\u8457\u306a\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u308b\u3000\u3068\u3044\u3046\u8ad6\u6587<\/p>\n\n\n\n<p class=\"has-small-font-size\">\u53c2\u7167URL<br>\u203b1 <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30826116\/\">Double-stranded sperm DNA damage is a cause of delay in embryo development and can impair implantation rates &#8211; PubMed<\/a><\/p>\n\n\n\n<p>\u307e\u305f\u3001DNA\u65ad\u7247\u5316\u7387\u306f\u5e74\u9f62\u3092\u91cd\u306d\u308b\u3054\u3068\u306b\u5897\u52a0\u3059\u308b\u50be\u5411\u304c\u3042\u308b\u3053\u3068\u3084<sup>\u203b\uff11<\/sup>\u3001\u305d\u306e\u4ed6\u3001\u751f\u6d3b\u7fd2\u6163\u306b\u3088\u3063\u3066\u60aa\u5f71\u97ff\u304c\u3067\u308b\u3053\u3068\u304c\u6307\u6458\u3055\u308c\u3066\u3044\u307e\u3059<sup>\u203b\uff12<\/sup>\u3002\u751f\u6d3b\u7fd2\u6163\u304c\u4e71\u308c\u3066\u3044\u308b\u3068\u4f53\u5185\u306b\u9178\u5316\u7269\u8cea\u304c\u84c4\u7a4d\u3057\u3066\u3057\u307e\u3044\u3001\u304b\u3089\u3060\u5168\u4f53\u306e\u7d30\u80de\u306b\u30c0\u30e1\u30fc\u30b8\u4e0e\u3048\u3066\u3057\u307e\u3044\u307e\u3059\u3002\u305d\u306e\u7d50\u679c\u7d30\u80de\u5185\u306e\uff24\uff2e\uff21\u306b\u30c0\u30e1\u30fc\u30b8\u3092\u4e0e\u3048\u308b\u3053\u3068\u306b\u306a\u308a\u3001\u5375\u5b50\u3084\u7cbe\u5b50\u306e\uff24\uff2e\uff21\u640d\u50b7\u306e\u304d\u3063\u304b\u3051\u3068\u306a\u3063\u3066\u3044\u3057\u307e\u3044\u307e\u3059\u3002<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"639\" height=\"481\" src=\"https:\/\/nippori-lc.jp\/blog\/wp-content\/uploads\/2025\/08\/image-4.png\" alt=\"\" class=\"wp-image-1619\" srcset=\"https:\/\/nippori-lc.jp\/blog\/wp-content\/uploads\/2025\/08\/image-4.png 639w, https:\/\/nippori-lc.jp\/blog\/wp-content\/uploads\/2025\/08\/image-4-400x300.png 400w\" sizes=\"auto, (max-width: 639px) 100vw, 639px\" \/><\/figure>\n<\/div>\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"722\" height=\"398\" src=\"https:\/\/nippori-lc.jp\/blog\/wp-content\/uploads\/2025\/08\/image-5.png\" alt=\"\" class=\"wp-image-1620\" srcset=\"https:\/\/nippori-lc.jp\/blog\/wp-content\/uploads\/2025\/08\/image-5.png 722w, https:\/\/nippori-lc.jp\/blog\/wp-content\/uploads\/2025\/08\/image-5-400x220.png 400w\" sizes=\"auto, (max-width: 722px) 100vw, 722px\" \/><\/figure>\n<\/div>\n\n\n<p class=\"has-small-font-size\">\u53c2\u7167URL<br>\u203b1\uff08<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC8761235\/\">Advanced Paternal Age and Sperm DNA Fragmentation: A Systematic Review &#8211; PMC<\/a>\uff09<br>\u203b2 <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/18281241\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/18281241\/<\/a><\/p>\n\n\n\n<p>\u4ee5\u4e0b\u306e\u70b9\u3067\u601d\u3044\u5f53\u305f\u308b\u65b9\u306f\u3068\u304f\u306b\u691c\u67fb\u306e\u5b9f\u65bd\u3092\u304a\u3059\u3059\u3081\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u904e\u53bb\u306b\u7cbe\u6db2\u6240\u898b\u3092\u6e2c\u3063\u305f\u304c\u3001\u6570\u5024\u304c\u826f\u304f\u306a\u3044<\/li>\n\n\n\n<li>\u7cbe\u6db2\u6240\u898b\u304c\u826f\u3044\u306b\u3082\u304b\u304b\u308f\u3089\u305a\u30011\u5e74\u4ee5\u4e0a\u598a\u5a20\u306b\u81f3\u3089\u306a\u3044\u30ab\u30c3\u30d7\u30eb<\/li>\n\n\n\n<li>\u4f4e\u53d7\u7cbe\u7387\u3084\u80da\u306e\u767a\u80b2\u4e0d\u826f\u3001\u6d41\u7523\u3092\u8907\u6570\u56de\u7e70\u308a\u8fd4\u3057\u3066\u3057\u307e\u3046<\/li>\n\n\n\n<li>\u592b\u5e74\u9f62\u304c40\u6b73\u4ee5\u4e0a\u306e\u65b9<\/li>\n\n\n\n<li>\u7cbe\u7d22\u9759\u8108\u7624\u306e\u6709\u7121\u307e\u305f\u306f\u624b\u8853\u6b74\u304c\u3042\u308b\u7537\u6027<\/li>\n\n\n\n<li>\u65e5\u3005\u306e\u751f\u6d3b\u306b\u30b9\u30c8\u30ec\u30b9\u3092\u611f\u3058\u3066\u3044\u308b\u3002\u7761\u7720\u304c\u3068\u308c\u3066\u3044\u306a\u3044\u3002<\/li>\n\n\n\n<li>\u55ab\u7159\u3001\u98f2\u9152\u304c\u591a\u304f\u3001\u904b\u52d5\u3084\u98df\u751f\u6d3b\u306b\u3064\u3044\u3066\u751f\u6d3b\u7fd2\u6163\u306e\u6539\u5584\u3092\u6307\u6458\u3055\u308c\u3066\u3044\u308b<\/li>\n<\/ul>\n\n\n\n<p>\u598a\u5a20\u3092\u76ee\u6307\u3059\u65b9\u3005\u306f\u4e8b\u524d\u306b\u7cbe\u6db2\u691c\u67fb\u3068DFI\u691c\u67fb\u3092\u4f75\u305b\u3066\u884c\u3046\u3053\u3068\u3067\u3001\u6b63\u78ba\u306a\u7cbe\u5b50\u306e\u72b6\u614b\u3092\u77e5\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u305f\u3081\u3001\u7d50\u679c\u7684\u306b\u598a\u5a20\u307e\u3067\u306e\u6700\u77ed\u30eb\u30fc\u30c8\u3092\u8fbf\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u3068\u601d\u3044\u307e\u3059\u3002\u7cbe\u6db2\u691c\u67fb\u306e\u969b\u306f\u305c\u3072\u691c\u67fb\u306e\u53d7\u8a3a\u3092\u3054\u691c\u8a0e\u304f\u3060\u3055\u3044\u3002<\/p>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u3053\u3093\u306b\u3061\u306f\u57f9\u990a\u90e8\u3067\u3059\u3002 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